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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKH
All Species:
18.18
Human Site:
S197
Identified Species:
50
UniProt:
Q86XP1
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86XP1
NP_690874.2
1220
134866
S197
N
V
C
R
E
S
L
S
G
V
T
S
H
G
L
Chimpanzee
Pan troglodytes
XP_001151474
1220
134870
S197
N
V
C
R
E
S
L
S
G
V
T
S
H
G
L
Rhesus Macaque
Macaca mulatta
XP_001114920
1167
129871
I181
L
A
S
I
G
K
D
I
I
E
D
A
D
G
I
Dog
Lupus familis
XP_534133
1182
132580
K188
V
R
A
T
N
N
C
K
W
T
T
L
A
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507672
1254
138458
S226
N
V
C
R
E
S
L
S
G
V
T
S
H
G
L
Chicken
Gallus gallus
XP_001232791
1333
149344
S303
N
V
C
R
E
S
L
S
G
V
T
S
H
G
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001108193
586
65385
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A8JQ65
1895
211641
S217
N
V
C
R
D
A
L
S
G
V
T
S
H
G
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202627
1158
127377
N182
G
Y
W
Q
A
S
K
N
G
C
G
S
P
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
62.2
90.7
N.A.
N.A.
N.A.
N.A.
82.3
76.8
N.A.
39
N.A.
34.9
N.A.
N.A.
51.5
Protein Similarity:
100
99.8
73.4
92.8
N.A.
N.A.
N.A.
N.A.
88.1
82.9
N.A.
43.2
N.A.
46.5
N.A.
N.A.
64.1
P-Site Identity:
100
100
6.6
6.6
N.A.
N.A.
N.A.
N.A.
100
100
N.A.
0
N.A.
86.6
N.A.
N.A.
26.6
P-Site Similarity:
100
100
20
20
N.A.
N.A.
N.A.
N.A.
100
100
N.A.
0
N.A.
100
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
12
0
12
12
0
0
0
0
0
12
12
0
0
% A
% Cys:
0
0
56
0
0
0
12
0
0
12
0
0
0
0
0
% C
% Asp:
0
0
0
0
12
0
12
0
0
0
12
0
12
0
0
% D
% Glu:
0
0
0
0
45
0
0
0
0
12
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
0
0
12
0
0
0
67
0
12
0
0
67
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
56
0
0
% H
% Ile:
0
0
0
12
0
0
0
12
12
0
0
0
0
0
23
% I
% Lys:
0
0
0
0
0
12
12
12
0
0
0
0
0
0
0
% K
% Leu:
12
0
0
0
0
0
56
0
0
0
0
12
0
12
67
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
56
0
0
0
12
12
0
12
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% P
% Gln:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
12
0
56
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
12
0
0
56
0
56
0
0
0
67
0
12
0
% S
% Thr:
0
0
0
12
0
0
0
0
0
12
67
0
0
0
0
% T
% Val:
12
56
0
0
0
0
0
0
0
56
0
0
0
0
0
% V
% Trp:
0
0
12
0
0
0
0
0
12
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _